By Car:

From the UK via the Channel Tunnel, or overnight from Portsmouth to St Malo or Poole to Cherbourgh.  There are good motorway connections from the ports via the E5 and E72, leaving at junction 7, Agen.  

By Air:

Toulouse and Bordeaux airports are both one and a half hours away.  Regular scheduled flights leave from Heathrow or Gatwick.

By Train:

There is an excellent rail service using the Eurostar and TGV from London Waterloo station to Agen via Lille.